Drafted in 2004 with the first overall pick by the San Diego Chargers, Eli Manning did not want to play for the Bolts, and he was quickly dealt to the New York Giants, where he would play his entire career.  A four-time Pro Bowl Selection, he would take the Giants to two Super Bowl Championships, both against the heavily favored New England Patriots, the first of which was when the Pats were undefeated going into the big game.  Notably, he was the Super Bowl MVP in both of their title wins.

Aqib Talib was the 20^thOverall Pick in 2008, but the former Kansas Jayhawk struggled early to live up to expectations.  Winning the starting job at Left Cornerback for the Tampa Bay Buccaneers in his sophomore year, Talib did well, but it was not until 2012, when he was traded to the New England Patriots where his star began to rise.

Zane Beadles was twice an All-MWC Selection when he played at Utah, and he stayed in the mountains when the Denver Broncos took him in the Second Round in 2010.

Sam Shields was undrafted in 2010, but the former Miami Hurricane found employment with the Green Bay Packers, the team that he helped as a rookie win Super Bowl XLV.