After winning the American League Rookie of the Year, Wil Myers was part of a monster three-team trade that sent him to San Diego for the 2015 Season.

Myers was not been the most consistent player since his arrival to the West Coast, but there have been flashes of brilliance.  An All-Star in 2016, Myers developed his power game that year, belting 28 Home Runs that year and 30 the year after.  The Centerfielder's best year to date is arguably the COVID-shortened 2020 Season, where he batted .288 with 15 Home Runs and was 16^th in MVP voting.  That was Myers' best time in San Diego, as his production slipped afterward before he left for Cincinnati as a Free Agent after the 2022 Season.

Myers had 134 Home Runs and 771 Hits with the team.

After eight seasons, most of which with the Milwaukee Brewers, Mark Loretta signed with the San Diego Padres for the 2003 Season, and he had the best run of his career as a Padre.

Loretta took over at Second Base for San Diego, and in 2003, he batted .314 with 13 Home Runs and 185 Hits, a very good year for him, but he had something better planned in 2004.  An All-Star for the first time, Loretta had career-bests in Runs (108), Hits (208), Doubles (47), Home Runs (16), RBIs (76), and the Slash Line (.335/.391/495), won the Silver Slugger and was ninth in MVP voting. 

Loretta was not able to recapture that in 2005 but did in 2006…though, by that time, he had already been traded to Boston.  With the Padres, Loretta batted .314 with 506 Hits.

The Hall of Fame career of Roberto Alomar began in 1988 with the San Diego Padres, and he did not take long to prove he was a star on the rise.

Alomar was fifth in Rookie of the Year voting, batting .266 with 145 Hits.  Improving that to 184 Hits and a .295 Average, Alomar swiped 42 bases, his high as a Padre.  A good defensive player, Alomar did not win a Gold Glove but was worthy of consideration during his stay in San Diego.  Alomar went to his first All-Star Game in 1990, again batting over .280, but this was his last year in Southern California.

Alomar was traded to Toronto after the 1991 Season, and would achieve greater success, winning two World Series Rings and multiple All-Stars.  He was inducted into the Baseball Hall of Fame in 2011.

Dave Dravecky began his baseball career with San Diego in 1982, making the starting rotation during his rookie year.  The southpaw was an All-Star as a sophomore, with a 14-10 year, and he followed that with back-to-back 2.93 ERA years and helped the Padres win the 1984 Pennant.

Dravecky continued to do well, but the struggling Padres traded him to the Giants.  Dravecky contracted cancer in his pitching arm, eventually resulting in its amputation.  Dravecky had a 53-50 Record with a 3.12 ERA with 456 Strikeouts with the Padres.