Mike Cuellar would become a World Series Champion and a Cy Young winner with the Baltimore Orioles, but he first turned heads when he was a Houston Astro.  Cuellar would go his first All-Star Game as an Astro in 1967, a season where he went 16 and 11.  Overall, in the four seasons he was in Houston (1965-68), he went 37-36 with 557 Strikeouts.

Known for being one of the more prolific Pinch Hitters of all-time, Denny Walling was a Houston Astro for 13 of his 18 seasons and was predominantly used against right handed pitchers.  Walling was especially effective with his bat in the cavernous Astrodome and the fact that he was capable of playing multiple defensive positions made him an asset for Houston.  He would have 726 Hits for the club.

Twice an All-Star as an Astro, Dave Smith was Houston’s closer for years, saving 20 games in six consecutive seasons.   He would record six seasons with a WHIP under 1.100 and would finish on the top five in Saves three times.

Dallas Keuchel joined the Houston organization as a seventh-round selection in the 2009 draft out of the University of Arkansas, a left-hander whose path to the big leagues was defined by a rapid three-year climb through the minors alongside fellow prospects Jose Altuve and J.D. Martinez. After debuting in 2012, he transitioned from a struggling young starter into the definitive ground-ball specialist of the American League, providing a specialized sinking fastball that few hitters could elevate.

The climb toward Keuchel’s historic 2015 peak was a study in high-frequency improvement and tactical refinement. After enduring a difficult introduction to the majors, he evolved into a frontline starter by 2014, earning his first of five career Gold Glove Awards for his elite defensive reliability. This period of rapid growth served as the essential lead-in to his most dominant run, showing that when a pitcher pairs a pinpoint changeup with focused intensity at the bottom of the strike zone, he can become a perennial award contender. By 2015, he had officially seized the role of the league’s premier southpaw, becoming a primary catalyst for the Astros' first postseason appearance in a decade.

That summer, he demonstrated a specialized ability to dismantle opposing lineups, recording a 20-8 record and a 2.48 ERA while leading the American League in wins and innings pitched. He showed the organization that he was a foundational winner, winning the Cy Young Award and finishing fifth in the MVP voting, a testament to his status as a certified ace. He possessed a rare, durable quality that allowed him to toss three complete games and two shutouts, providing the steady-state production required to turn Houston into a powerhouse. While he battled through injuries in the following years, he returned to All-Star form in 2017, posting a 14-5 record and a 2.90 ERA to help secure the franchise’s first-ever World Series title.

After amassing a 76-63 record and 945 strikeouts while wearing the Houston colors, Keuchel rejected a qualifying offer from the club, leading to a long wait on the open market due to draft-pick compensation rules. He eventually signed a one-year deal with the Atlanta Braves in June 2019.