The 16th Overall Pick in the 2000 Draft, Julian Peterson carved out a good career in the National Football League.  Winning the Left Outside Linebacker job midway through his rookie year with the San Francisco 49ers, Peterson would go to the Pro Bowl in 2002 and 2003, the last season seeing him earn First Team All-Pro accolades.  He would later sign with the Seattle Seahawks in 2006 and was a Pro Bowl Selection in all three seasons playing there.  He would go to Detroit for his final two years, and he accumulated 51.5 Sacks over his career.

Although he became known for the sexual assault case in 2014 (which alleged that he was a serial rapist), Darren Sharper was known mostly on the gridiron for his defensive skills and for leading the National Football League in Interception Return Yards three times.

Chris Samuels was the Outland Trophy winner at the University of Alabama, and the Washington Redskins chose him 3^rd Overall in 2000.  It turned out to be an excellent choice, and Washington would be the only team that Samuels played for in his ten-year career.  

Richard “Rip” Hamilton brings a rare resume where he won both the NCAA Championship (UConn) and in the NBA (Detroit) and was a vital member to both titles. Hamilton earned the NCAA Final Four MVP in the Connecticut title and in the 2004 Pistons Championship averaged over 20 Points per Game. “Rip” was a three time All Star, a slick shooter, and had he had a better defensive game Hamilton might be a considered a shot for the Hall of Fame. As it looks now, it might be a difficult road.