Although he was considered undersized for a Defensive Tackle, it did not take Kyle Williams long to crack the Buffalo Bills starting lineup.  Once Williams did, he would stay there for the duration of his 13-year career and he would work his way into being one of the best in the National Football League.  A Bill throughout his career, Williams was a six-time Pro Bowl Selection and his 48.5 Quarterback Sacks is the franchise leader among Defensive Tackles.  Williams will not go down in Buffalo Bills history as one of their best defensive players but his leadership and popularity had few peers.

Nate Odomes was another key member of the Buffalo Bills four AFC Championships and was the Interceptions leader in the National Football League in 1993.  The two time Pro Bowler would record key interceptions in both the famous Frank Reich comeback game and in Super Bowl XXVII.  WIth the Bills, Odomes secured 26 Interceptions.

Three time First Team AFL All-Pro Cornerback, Butch Byrd still holds the Buffalo Bills records for Interceptions (40), Interception Return Yards (666) and Interceptions returned for Touchdowns (5).  Byrd was also a solid punt returner and was a named to the AFL All-Time Second Team.  Byrd also helped the Bills win back-to-back AFC Titles in 1964 and 1965.

A member of the 1964 and 1965 AFL Championship Teams, Defensive Tackle, Tom Sestak was a master pass rusher and was chosen for the All-Time AFL Team.  Sestak would only play for the Buffalo Bills and was a four-time AFL All-Star.  Sestak led the AFL (unofficially) in Sacks in 1964 with 15.5 and took down the Quarterback 52 times in total.

Buffalo inducted Sestak into their Wall of Fame in 1987.