The San Diego Chargers used their First Round Pick in 1979 to obtain Kellen Winslow, a Tight End from Missouri.  Injuries held him to seven Games that year, but over the next four years, he was easily the best Tight End in the National Football League.

After signing with the San Diego Chargers in 1962 (instead of the Detroit Lions of the NFL), John Hadl shared Quarterback duties with Tobin Rote, where he backed him up as the Chargers won the 1963 AFL Championship.

Antonio Gates had a good career a Kent State, but it did not result in any NFL team drafting him in 2003.  The San Diego Chargers signed him, and he would wear the lightning bolt on his helmet for the entirety of his 16-year career.

Ron Mix had a spectacular career at USC, and to nobody's surprise, he was a First Round Pick in the NFL.  The problem was that it was the Baltimore Colts on the East Coast who chose him, and the native of Los Angeles wanted to stay close to home.  In the AFL, the Boston Patriots took him in the first-ever draft of that league, but a trade to the Chargers allowed him to stay close to home.