Off-field arrests during his collegiate career at Oklahoma State forced Tyreek Hill to finish his college tenure at West Alabama, making NFL front offices hesitate on draft day. Recognizing his world-class track speed, Kansas City selected the explosive playmaker in the fifth round (165th overall) of the 2016 NFL Draft—a decision that instantly reshaped Andy Reid’s perimeter offense and special teams units.

Hill made an immediate national impact during his rookie campaign as the league's most fearsome return artist. Leading the NFL with 592 punt return yards and returning two punts and one kickoff for touchdowns, he added 860 total scrimmage yards and 12 combined touchdowns to secure a Pro Bowl nod and consensus AP First-Team All-Pro selection as a return specialist.

As Patrick Mahomes stepped into the starting quarterback role, "Cheetah" fully transitioned into a dominant, primary wide receiver. Hill broke out with 1,183 receiving yards in 2017 before exploding in 2018 with 87 receptions for a career-high 1,479 yards and 12 receiving touchdowns—earning his second First-Team All-Pro nod as Kansas City advanced to the AFC Championship Game.

A clavicle injury sidelined him for four games during the 2019 regular season, but Hill remained a lethal big-play weapon when healthy. He capped off that campaign on pro football's biggest stage in Super Bowl LIV, hauling in nine passes for 105 yards—highlighted by a famous 44-yard catch on "Jet Chip Wasp" on 3rd-and-15—to spark Kansas City's dramatic fourth-quarter comeback victory over San Francisco.

Hill continued his aerial dominance over his final two seasons in Missouri, recording 1,276 receiving yards and a career-best 15 touchdowns in 2020 (earning a third First-Team All-Pro honor) followed by a franchise-record 111 receptions in 2021. In March 2022, Kansas City traded the star wideout to the Miami Dolphins in exchange for a massive haul of five draft picks.

In Kansas City, Hill generated 479 receptions for 6,630 receiving yards, 719 rushing yards, 8,745 all-purpose yards, and 67 total touchdowns.