A First Round Pick from Mississippi, Freddie Joe Nunn seemed to bounce from Defensive End to Linebacker depending on the need in his first nine years in the NFL as a Cardinal.

A really good player but never was named a Pro Bowler or All-Pro, Nunn was at his best as a pass rusher, as shown by his 14-Sack year in 1988, the first year of the Cards' relocation to the desert.  Had Nunn received a more defined and consistent role with the Cardinals and not endured legal issues (he was arrested multiple times), his profile in Cardinal history would be more significant.  It also did not help that the St. Louis/Phoenix were hardly world-beaters when he played there.  After nine seasons, Nunn departed for the Colts, where he played three years to close out his career.

Following Nunn's departure, he had the franchise record 66.5 Sacks, a record that stood until it was broken by Chandler Jones in 2021.

The first man to win back-to-back Sun Bowl MVPs and have his number retired at New Mexico State, Charley Johnson was drafted late (10^th Round) of the 1960 Draft, seeing limited action in his rookie year, but became the Cardinals starter in his second season. 

Johnson may not have ever appeared in a playoff game, but in '63 and '64, he had nine wins each in 14-game Seasons and was one of the top QBs in the league.  A Pro Bowl selection in 1963, Johnson led the NFL in Completions (223) and Passing Yards (3,045), though he also had 24 Interceptions against 21 Touchdown Passes that year. 

Johnson remained St. Louis’s starting Quarterback until the emergence of Jim Hart in 1969, and he was traded to the Houston Oilers.  Overall, with the Cardinals, Johnson compiled a TD-INT ratio of 108-110 and 14,928 Yards.

With the Fifth Overall Pick in the 1981 Draft, the St. Louis Cardinals selected E.J. Junior, who was the second Linebacker taken behind someone you may have heard of; Lawrence Taylor.  Junior did not have Taylor’s career (who could?) but the Cardinals got a lot of good football from the eventual College Football Hall of Fame inductee.

Junior won the starting job during the season and, by the mid-80s, was one of the best interior Linebackers in the NFC.  His best season was in 1984 when he was a First Team All-Pro and began a two-year run of Pro Bowls.  From 183 to 1985, Junior had eight Interceptions and 19.0 Sacks, and though he tailed off afterward, he was still a solid NFL player.

He left the Cardinals behind in 1988, joining Miami as a Free Agent.  The Cardinals were not significant in the 1980s, but this does not detract from Junior's work in St.Louis/Phoenix.

In 2002, Carson Palmer was the best Quarterback in College Football, winning multiple awards and going number one overall in the Draft.  Fast forward a decade later, and Palmer was on his third team (Arizona), and despite the two Pro Bowls, was considered a minor disappointment based on the initial hype.  It was with the Cardinals that he eventually had the best season of his life.

Palmer threw for 4,274 Yards in 2013, finishing eighth in that stat, and became the first QB to throw for 4,000 Yards in a year for three different teams.  A torn ACL took him out of half of 2014, but his 2015 was electric.  Palmer was second in MVP voting to Carolina's Cam Newton and had career-highs in Passing Yards (4,671) and Touchdown Passes (35) while topping the league in Yards per Attempt (8.7), Yards per Completion (13.7) and QBR (76.4).

Palmer had another excellent year in 2016 (4,233 Passing Yards & 26 TDs) but a broken arm in Week 7 of 2017 ended his campaign, and eventually his career, as he retired in the off-season.  With Arizona, Palmer had 16,782 Yards and 105 Touchdowns, and entered their Ring of Honor in 2019.