Camilo Pascual left Cuba in 1951 at the age of 17, and a year later, he was part of the Washington Senators’ farm system. Pasucal was impressive and made the Washington main roster in 1954.

Pascual was largely unimpressive in his first few years, but he came of age in 1959, when he went 17-10 and led the American League in Complete Games (17) and FIP (2.44).  The Cuban was an All-Star for the first time and would be in four of the next five seasons.

The Senators relocated to Minnesota, becoming the Twins in 1961, and in the first three years of the franchise's relocation, he was the league-leader in Strikeouts.  The Twins won the American League Pennant in 1965, of which Pascual was a part, but he was no longer the same Pitcher by this time.

He was traded back to the city of Washington and the new version of the Senators at the end of the 1966 season, and he had a pair of 12 Win years.  He finished his career with Cincinnati, Los Angeles, and Cleveland, retiring in 1971 with a 174-170 record with 2,167 Strikeouts.

Camilo Pascual reached the Majors with Washington in 1954 at age 20, known for his back-arching windup and a devastating curveball that Ted Williams called the "most feared" in the American League for nearly twenty years.

Between 1954 and 1958, Pascual showcased a specialized ceiling as a strikeout threat, although his win-loss record was often affected by the team's poor performance. In 1959, he reached a career peak, leading the American League with 17 complete games and 6 shutouts, earning his first of seven All-Star nominations.

After the franchise moved to Minnesota in 1961, Pascual enjoyed a three-year period of dominance that remains a significant benchmark in team history. He led the American League in strikeouts for three straight seasons (1961–1963) and achieved consecutive 20-win seasons. In 1963, he went 21-9 with a 2.46 ERA and led the AL in complete games for the third time. During this peak, he was a reliable, high-volume pitcher whose durability enabled him to pitch over 240 innings each year, making him a specialized ace for the Twins as they grew into a pennant contender.

In 1966, the final year of his primary tenure, he transitioned into a veteran role. Before that, he played a crucial part in the 1965 World Series team. Although an injury caused him to miss much of that championship summer, he made his mark on team history on April 27, 1965, by hitting a grand slam, one of the rare pitchers to do so.

Ironically, he was traded to the second incarnation of the Washington Senators in 1967, thus ending his stay in the Twin Cities.  Pascual went 145-141 for the franchise, fanning 1,885 Strikeouts.  The Twins inducted him into their franchise Hall of Fame in 2012.