Every new NFL season brings a fresh set of storylines, breakout stars, and a healthy dose of wild-card chaos. 

But when it comes to early bets for Offensive and Defensive Player of the Year, a few names already have the spotlight – and a few others are quietly coming for it.

Here’s a breakdown of five types of contenders to watch as the 2025 season kicks off, including heavy-hitting favorites and unexpected long shots.

The Offensive Favorite: Saquon Barkley (+500)

After a comeback season that ended with hardware in hand, Saquon Barkley is back on top of the board. Now in Philly and playing behind one of the best O-lines in football, Barkley has everything he needs to repeat as Offensive Player of the Year: talent, opportunity, and a whole lot of momentum.

The Eagles are expected to run the ball heavily this season, especially with a new offensive coordinator focused on ground-and-pound efficiency. If Barkley stays healthy (always the big “if”), he could easily rack up 2,000+ scrimmage yards and double-digit touchdowns again. He’s the chalk for a reason.

The Defensive Favorite: Aidan Hutchinson (+700)

At just 24, Aidan Hutchinson is quickly becoming the face of the Lions’ defense – and maybe even the NFC North. 

He’s the betting favorite for Defensive Player of the Year, and it’s not hard to see why. Last season, Hutch racked up 11.5 sacks, 3 forced fumbles, and a whole lot of QB pressure that doesn’t always show up on the stat sheet.

The Lions are building a legitimate contender, and with a high-motor pass rusher like Hutchinson, they could dominate the trenches all year. 

If he cracks 15+ sacks and anchors Detroit’s playoff push – the Lions have already asked for rule changes with this in mind – expect his name to stay near the top of this list.

The Dark Horse: Nico Collins (+1800 to +2000)

If there’s one wide receiver with “breakout superstar” written all over him, it’s Nico Collins. 

Collins quietly posted 1,297 yards and 8 touchdowns last season with rookie QB C.J. Stroud, on just 80 catches. That kind of efficiency turns heads, especially when you're not even the first or second name people mention on the board.

Another year of chemistry with Stroud and a Texans offense that looks more dangerous by the day will mean that Collins has real OPOY potential. 

At +2000 in some books, he’s criminally undervalued. If he hits 1,500+ yards and double-digit TDs, don’t say we didn’t warn you.

The Veteran: Christian McCaffrey (+2000)

Let’s not forget about the human highlight reel that is Christian McCaffrey. 

After years of injuries, CMC looked like his old self last season – and then some. He led the NFL in total touchdowns, torched defenses on the ground and through the air, and helped the 49ers look like world-beaters.

At 28, he’s not the young gun anymore, but he’s still a game-changer. San Francisco’s offense is built to give McCaffrey touches in space, and that means fantasy owners (and award voters) are going to see his name a lot. 

The wear-and-tear risk is there, but at +2000, the upside is still worth a long look.

The Long Shot: Fred Warner (+7,500)

You may look at Fred Warner’s odds of +7500 for Defensive Player of the Year and think what’s the point betting on such a remote chance – after all, you may as well bet on roulette (which has shorter odds) at one of the best live casinos the internet has to offer.

Well, while Warner might not top the highlight reels, ask any coach or analyst who the best linebacker in the game is, and you’ll probably hear his name.

Being a true defensive quarterback, Warner controls the middle of the field like a chess master. He’s the kind of player who doesn’t always pile up sacks but dominates the games with positioning and game IQ.

So, why the long odds? Because voters love flashy stats, and Warner’s game is all about the subtleties. If the 49ers have another top-tier defensive season and Warner picks up some momentum with a few splash plays early, he could finally get his flowers. 

At +7500, he’s the kind of pick that could make you look like a genius in January.