501. The Breeders

They may have formed as somewhat of an afterthought by artists who felt creatively stunted by their main groups (The Pixies and Throwing Muses respectively), but the American Alternative group, the Breeders had a shot to be one of the top bands of the 90’s.  Their acclaimed 1993 album, Last Splash showed off their skills and a prime spot on that year’s Lollapalooza tour.  Had they followed up, they likely would have been much bigger than they were.