Jefferson was an All-Rookie who was fourth in Receiving Yards (1,001) and was the NFL-leader in Receiving Touchdowns with 13. He would go to the Pro Bowl as a rookie and be one again in the next two seasons. In 1979, he again broke 1,000 Yards (1,090) with an even 10 Touchdowns. This season, Jefferson was a First Team All-Pro and would be again in 1980, when he had the season of his life. Jefferson's '80 campaign would see the Wide Receiver in Yards (1,340) and Touchdowns (13).
Jefferson felt underpaid, and when the Chargers refused to renegotiate his contract, Jefferson, in turn, refused to play for San Diego. Jefferson was dealt to Green Bay in September of 1981. Jefferson was only a Charger for three seasons, but it was far and away the best run of his career. He would accumulate 3,431 Yards and 36 Touchdowns.