Playing his college ball at USC, Casey arrived in the NFL to Tennessee as a Third Round Pick in 2011.  Casey became an immediate starter at Right Defensive Tackle, and was arguably robbed of a Pro Bowl in 2013, a year he had a career-high 10.5 Sacks.  He would finally get that first Pro Bowl in 2015, which would lead to four more in succession.

A Titan for all but his final year in football, Casey had 51.0 Sacks, all in Tennessee, and was a large part of the Titans defensive turnaround in the 2010s.

Casey, was also known for his philanthropy, and was the winner of two community service awards.